Ubiquitin not only serves as a tag but also assists degradation by inducing protein unfolding
نویسندگان
چکیده
منابع مشابه
Ubiquitin not only serves as a tag but also assists degradation by inducing protein unfolding.
Protein ubiquitination controls the cellular fate of numerous eukaryotic proteins. Despite its importance, many fundamental questions remain regarding its mechanism. One such question is how ubiquitination alters the biophysical properties of the modified protein and whether these alterations are significant in the cellular context. In this study, we investigate the effects of ubiquitination on...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2010
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0912335107